Real Madrid have injured Brazilian striker Vinicius Junior and Spanish defender Lucas Vazquez, the club announced on Monday on its official website.
Both players were injured in Real's 4-3 defeat to Barcelona on Sunday.
Vinicius has a left ankle injury while Vazquez has a left thigh injury.
The 33-year-old Vazquez will miss Real's next La Liga match against Mallorca. Meanwhile, it is still unknown how long Vinicius will be out.
Real Madrid has had problems with numerous injuries to its players throughout the season.
In addition to Vinicius and Vazquez, David Alaba, Eduardo Camavinga, Ferland Mendy, Dani Carvajal, Eder Militao and Aurelien Tchouameni are also injured.
