Lionel Messi suffered a "minor muscle injury" in his right leg in Inter Miami's win over Necaxa on Saturday.
The Argentine's team, Inter Miami, has confirmed the injury, but without specifying how long Messi will be out of action.
According to the American club's statement, the absence will depend on Messi's progress and the success of the treatment.
Messi was substituted in the 11th minute of the weekend's match. He was in fine form, having scored twice for Inter Miami in six of his last seven games.